Human Growth Hormone (HGH) for "Dummies"
By HRT Medical Team profmark@gmail.com

Keywords: Growth Hormone, Human Growth Hormone (HGH)3, Somatotropin5, Sermorelin, HGH Therapy.

Introduction to Human Growth Hormone

As one cocky news reporter put it, "Unless you're sleeping under a rock, you've probably heard about Human Growth Hormone". We see HGH mentioned on TV news or have read about it in all major newspapers and magazines, or on the Internet.

Athletes and famous Hollywood actors are using HGH for everything from sports enhancement, anti-aging, skin, brain, muscle, joint and organ regeneration, to turning back the clock, or for simply for the purpose of looking and feeling younger inside and out.

Internationally recognized Rocky and Rambo star, Sylvester Stallone, was busted in Australia with HGH and allegedly "misplaced" his doctor's prescription. He was reprimanded, and had to pay a $2,000 fine. Stallone, who is in his 60's, but has the energy and vitality of a 35 year old athlete, credits part of his quality of life directly to HGH. Mr. Stallone has publicly stated to the media, to paraphrase, that in 10 years (or less) HGH will become an over the counter product. When the smoke of controversy clears, and congress looks closer at the thousands of research studies on HGH, Stallone's statements might prove true, until then, a doctor's prescription is required for HGH.

Since "winning is everything," HGH is being used by many prominent professional and Olympic athletes in every sport known to humankind, for significant performance enhancement (yes, even "brain sports", such as chess and poker), more specifically, to create a real quantifiable advantage over competitors. But, use of HGH is not FDA approved for sports enhancement or body building, and therefore, HGH use is illegal for these two specific purposes, which causes many people to think HGH is completely illegal. HGH is, however, not illegal for adults over the age of 30 seeking genuine anti-aging and regeneration medicine to overcome HGH deficiencies, aka "premature" aging.

The two search engines, Google and Yahoo, who control about 90% of total internet searches, show the terms HGH or Human Growth Hormone, are searched beyond 20,000 times per day online!

As a result of the explosive popularity of HGH, to be used for more than just genuine medical anti-aging purposes, congress and the FDA are holding hearings and creating even more controversy over this very misunderstood, but amazing, protein called Human Growth Hormone.

HGH3 Information

The Big Picture: "What is HGH?" is becoming a very popular question, since almost every other day, HGH is mentioned in the media regarding its use by athletes, or breaking research emerges concerning the benefits of its use.


Somatotropin5 or Growth Hormone (GH)


More popularly known as HGH or Human Growth Hormone, is created in the base and center of the brain, more specifically, in the rear portion of the anterior lobe of the Pituitary Gland12. The Pituitary Gland has two primary lobes, the anterior or front lobe and posterior or back lobe. HGH is made in the back of the front lobe of the Pituitary Gland.







HGH is a delicate, unique and important hormone protein, which is the largest in the body, and has a variety of beneficial purposes in the human body. The most important feature is the stimulation of the growth, development and regeneration of healthy cells throughout the human body.



Left Side View of the Center Brain Region













Virtually every organ and system in the body is dependent on HGH for proper growth, development and function, therefore HGH is considered by many specialized medical experts in the field of anti-aging, longevity and cell regeneration medicine, to be the master hormone.


"What is a Hormone2?" A hormone (from the Greek "impetus" or a moving force; impulse; stimulus) is a chemical messenger that carries a signal from one cell (or group of cells) to another, via the blood. In general, hormones regulate the function of their target cells - the cells receiving the hormone. The action or net effect of hormones is determined by a number of factors, including its pattern of release into the human body, and the response of the receiving cells2.


"What does Human Growth Hormone look like?" HGH is a protein hormone made up of a chain of 191 amino acids, also known as a polypeptide (poly is Latin meaning 'many' - many peptides - many amino acids), which form a circular shape.

See the picture below / next page.


The Largest Protein in the Human Body



The Master Human Growth Hormone (HGH) Molecule3






"How is Human Growth Hormone made in the Human Body?" HGH is created and secreted into the bloodstream by the anterior (back part) lobe of the Pituitary Gland (which looks like a garbanzo bean) at the central base of the brain.


More specifically, in the rear portion of the Pituitary Gland, there is a kind of stack or sack of cells called Somatotropes, which make up about 40 to 50% of the anterior (back) of the Pituitary Gland, these cells act as a factory, pumping out this very important HGH protein.









The Human Growth Hormone (HGH) On and Off Switch


There seems to be two or more factors regulating the release, decrease and cease, of HGH. The Hypothalamus in the bottom (base) back of the brain, metaphorically acts to a great extent, as the on and off switch of HGH production.





Research on how to Stop HGH Production Permanently


In a research study by scientist Reichlin and his colleagues1, where the connection from the Hypothalamus11 to the Pituitary Gland was cut off (sectioned off), the Pituitary stopped producing healthy levels of HGH. This showed that the Hypothalamus, which produces the Growth Hormone Releasing Hormone (HGRH), is the dominant source of stimulating the Pituitary Gland to produce HGH. Also see: www.sermorelin.com regarding using the hormone: Growth Hormone Releasing Hormone to stimulate HGH release in the body (more affordable approach to increasing HGH in the body).


"The HGH ON Switch" The Hypothalamus plays an important role in HGH production and produces GHRH (also see Sermorelin), the precursor to stimulate HGH production in the Pituitary Gland. In other words, or laymen's terms, the Hypothalamus uses GHRH (growth hormone releasing hormone) to metaphorically tell the Pituitary Gland HGH "Factory", to kick-start the HGH assembly line production.


"The HGH OFF Switch" The Hypothalamus and body also play a role in the production of somatostatins (the OFF switch or simply HGH "Blockers"), to shut down or decrease HGH production in the Pituitary Gland. In laymen's terms the body releases somatostatins to tell the HGH assembly line to shut off.


"How is HGH released in the body and what is its frequency?" HGH is primarily released in pulses that take place during the beginning phases of sleep, with the highest release at the latest stages of sleep, which is why it is important to get a minimum of eight hours of restful sleep. People who do not get proper sleep have shorter life spans and sometime suffer from HGH deficiencies. During the 24-hour cycle of the day, HGH is released in smaller pulses, about 30 in total.


"What happens when HGH is released in the body?" Once HGH is released by the Pituitary Gland, it circulates in the bloodstream, throughout the body and the brain, and is eventually absorbed by the liver, where it is converted into growth factors, the most important one being IGF-1. Growth hormone is rapidly converted in the liver, to a powerful growth-promoting metabolite, an insulin-like growth factor - Type 1 (IGF-1, also referred to as Somatomedin C).



IGF-1 Insulin like Growth Factor One
IGF-1 causes most of the effects associated with HGH. It is measured in the blood to determine the level of growth hormone secretion. Most of the beneficial effects of HGH are directly attributable to its stimulation of IGF-1.
These growth factors are the messengers that carry the messages to the cells of the body. This communication regulates the growth of cells, telling them when to live and when to die. Cell reproduction slows down with aging, unless the cells are prompted by the growth factors of HGH.
Therefore, it could be said that HGH is the precursor of IGF-, that is to say, HGH is what stimulates the body (the liver) to produce IGF-1.



HGH Human Growth Hormone Replacement Therapy
Using a Pre-Cursor Secretagogue Analog (Sermorelin)
Secretagogue10 is a substance that promotes secretion, for instance the Secretagogue for HGH production, i.e. the substance that tells your Pituitary Gland to increase HGH production is GHRH (growth hormone releasing hormone) which comes from the hypothalamus.
Sermorelin (www.sermorelin.com) is a polypeptide chain that mimics the effects of GHRH (the substances that naturally tell your Pituitary Gland to increase HGH production.
GHRH Therapy: Sermorelin therapy, is an HGH "Secretagogue" delivered through subcutaneous Injection - GH-RH (1-29).

Growth hormone deficiency in adults occurs when the naturally occurring Pituitary hormone known as HGH is produced in inadequate quantities, with a resulting deficiency in growth hormone and IGF-1 levels in the bloodstream. Growth hormone deficiency includes a spectrum that ranges from a complete lack of growth hormone through varying degrees of partial growth hormone deficiency. Most people after the age of 25 to 30, begin a process of HGH deficiency, which accelerates at a loss rate of 1% to 2% per year, depending on ones own genetic makeup, diet, exercise and lifestyle.
In contrast to supplementing the growth hormone deficiency through injections of exogenous recombinant HGH, another therapy, GH-RH therapy, involves the use of GH-RH injections which cause and stimulates the body's Pituitary Gland to secrete greater quantities of naturally produced HGH (Sermorelin injections). The body, therefore, naturally produces its own growth hormone to supplement the deficiency as a result of GH-RH therapy.
Sermorelin is the acetate salt of an amidated synthetic amino acid polypeptide, consisting of the first 29 of 44 amino acids of naturally occurring HGH-releasing hormone (GH-H) in the body.
Sermorelin Acetate is the last of the hypothalamic-releasing hormones (stimulates hgh) to be identified and characterized, and represents the shortest fragment of GH-RH known to possess the full biological activity of the parent hormone known as the HGH-releasing hormone (GH-H) growth hormone releasing hormone.
In contrast to increasing growth hormone levels by the injection of biosynthetic or Bio-identical HGH, GH-RH injections increase plasma growth hormone concentrations in patients with idiopathic growth hormone deficiency, by directly stimulating the Pituitary Gland to release natural HGH. Sermorelin acetate for injection (GH-RH ) is similar to natural GH-RH. with respect to its ability to stimulate HGH secretions in humans.
Sermorelin is an affordable approach to increasing HGH in the body for those who are price sensitive.
GH-RH for injection has been effective in the treatment of growth hormone deficiency in children. The clinic anticipates that GH-RH will also be effective in the treatment of adult growth hormone deficiency because it has been effective in the treatment of children, and because HGH has already proven itself to effective in cases of adult growth hormone deficiency. The GH-RH used by the clinic has been studied for 12 years in more than 70 clinical trials, in over 2,600 child patients, totaling more than 485 patient years of treatment.
Growth hormone releasing hormone for injection was approved for use in children with growth hormone deficiency (GHD), by the FDA in 1997, and became available to the clinic in 1998. It is an experimental clinic treatment with regards to adult patients who are prescribed about half the dose of a small child. Prior clinic approval is required to participate in the adult clinical trial program conducted by the clinic. This therapy has great potential for adults who have growth hormone deficiency, and seek to reverse the effects of aging, or treat a medical disorder. A patient who is dissatisfied with the results obtained through GH-GH therapy, may elect to be treated thereafter with HGH replacement therapy, or vice versa.



Human Growth Hormone Declines with Aging
The decline of growth hormone with age, is directly associated with many of the symptoms of aging, including cardiovascular disease, increased body fat, osteoporosis, wrinkling, gray hair, decreased energy, reduced sexual function and interest, and other pre-mature aging symptoms. Many of these symptoms have been found in younger adults who have growth hormone deficiency.
Research over the last 40 years confirms the decline of HGH as we age in our adult years, and the decline of HGH production accelerates as we get older, therefore, as we age after the age of 30, our bodies are not stimulating the regeneration of new healthy cells as fast as they are dying off, and as a net result, aging seems to be the process of our bodies slowly dying faster, then it can replace itself with healthy cells at first, and the dying process accelerates as we continue age.
HGH is produced at a rate that peaks during adolescence, when accelerated growth occurs. Growth hormone secretion decreases with age in every animal species tested, thus far. In humans, the amount of growth hormone after the age of 25 to 30, declines about 14% per decade (or 1% to 2% per year), therefore, total daily growth hormone production is reduced dramatically with age. In numerical values, we produce on a daily basis of about 500 micrograms of growth hormone at age 20, 200 micrograms at age 40, and 25 micrograms at age 80. At age 40 our growth hormone production is only 40% of what we produced at age 20. The fall in IGF-1 levels with age is identical to the decline of growth hormone.
More research and scientific experiments have shown that by the age of 40, our HGH production is down to 50% of youthful levels. By the age of 55 it sinks to 20%, which is not much more than someone in their 80's can produce.










Human Growth Hormone Decreases
Significantly after the age of 35 to 45
Scientists do not know the exact reason why persons over the age 35 to 45 tend to incur such a significant decrease in HGH growth hormone secretion from the Pituitary Gland, with the result causing symptoms of aging, andropause i.e. HGH deficiency.

Some medical research has revealed that the aging Pituitary somatotroph cells can still secrete as much growth hormone as the young somatotroph cells, if they are properly and adequately stimulated. As a result, some researchers have come up with several theories regarding aging resulting from HGH-related deficiency.






HGH "Blockers" (called Somatostatin5) increase with age
Some research scientists believe the problem of HGH deficiency lies with somatostatin (HGH "blockers"), the natural inhibitor (blocker) of HGH. Somatostatin has been found to increase in population within the body with age, and may act to block the pituitary's release of HGH. When researchers eliminated somatostatin production in old rats, they found growth hormone secretion, as great as those of young rats. This might indicate, theoretically, that the Pituitary Gland has a life-long ability to produce any healthy level of HGH we might desire.






HGH Stimulators Decrease with Age
A second theory concerning the decrease of HGH as we age is that the precursor hormone, growth hormone-releasing hormone (GH-RH), which stimulates HGH release by the Pituitary Gland, becomes less sensitive to signals from the Hypothalamus. Hence, insufficient GH-RH is released, resulting in a decrease of growth hormone secretions over time and age. See Sermorelin and the section on Growth Hormone Releasing Hormone.



The Body Requires More HGH as we Age or
the Body Loses its Ability to Utilize HGH as we Age
A third theory concerning HGH decline or deficiency is that, not only does the growth hormone secreted and available to receptors in our cells decrease with aging, but that the cell receptors become more resistant and less responsive to the HGH. Under this theory, aging can be viewed as a disease of growth hormone resistance within our cell receptors, similar to the way in which diabetes is a disease of insulin resistance.
The Benefits of Replacing HGH with Injections or
HGH Replacement Therapy


HGH, although very controversial, is considered by some scientists, doctors and researchers, to be one of the single most important protein/hormones in human development, health, regeneration, wellness and longevity. A growing number of Anti-Aging, Longevity and Cell Regeneration doctors swear by HGH and consider HGH replacement therapy to be a revolution in medicine.


Benefits of HGH
Most Importantly, clinical evidence and recent medical research clearly demonstrate that by replacing HGH in IGF-1 deficient adults, we can significantly eliminate premature aging symptoms, reverse the biological effects of aging, reduce body fat, increase lean muscle mass, strengthen the immune system, improve sexual performance and libido, lower blood pressure, lower cholesterol, restore hair color and growth, increase bone tissue, strengthen the heart, regenerate organs and increase energy.

There is no other substance known to medical science that has such extensive and well documented ability to deter and reverse the aging process as HGH.
In reviewing the benefits of growth hormone therapy listed above, it is difficult to believe HGH could have so many beneficial effects. However, as we examine more closely the evidence accumulated by medical research and the interaction between growth hormone and the various bodily systems and cell regeneration that affect the areas benefited, we develop an understanding as to how an increased level of growth hormone results in so many beneficial effects on the entire body.
Some studies have suggested HGH replacement therapy might possibly extend the human lifespan 10 to 20 years, as long as a health conscious lifestyle is included as a part of the doctor monitored HGH therapy program.




Bone Density and HGH


During growth hormone therapy, there is a definite improvement in bone density. One study showed an increased bone mass of 2% per year.




Skin and HGH


Growth hormone restores abnormal low levels of extra cellular fluid. This cellular dehydration is implicated in many of the signs of aging. By replenishing this extra cellular fluid, skin becomes thicker and wrinkles become less noticeable. Also, there is normalization of kidney function and improvement in sweating capacity.


Look closely at the skin of younger people and older people, you will notice several factors which give the indication of age. 1. smoothness of the skin 2. thickness of the skin 3. discoloration and age spots 4. wrinkles 5. suppleness among other factors, HGH has been shown to shift human skin towards a more vitality and youthfulness. Children, teenagers and young adults with growth hormone deficiency have experienced the signs of premature aging of the skin, and skin more closely resembles the skin of significantly older people.




Weight Management and HGH


Growth hormone induces decomposition of adipose tissue. The adipose cell volume will decrease significantly. Metabolism is increased, which results in the degradation of fat. In addition, cholesterol is lowered.


There is consistent improvement in this parameter with a usual 10% increase in lean body mass, and 5-10% decrease in body fat. Fat loss was greatest in the abdominal region. The alterations in body composition are reversed. The lean body mass increases, as the adipose tissue decreases. This accounts for the fact that there may not always be an overall weight loss because of the increased muscle mass. In addition, HGH affects the liver, kidneys, spleen, skin and bone, and is protective against atrophy, by causing re-growth of tissue.






HGH for Sale, Buying HGH, Getting HGH


Acquiring HGH requires a prescription from a medical doctor. Many people who look for an easy route to get human growth hormone look to black market Mexican and Chinese sources, these sources are not as potent and may contain harmful substances in them. Some people have gotten infections or died as a result of using black market HGH.

Do not go the illegal route, the legal route is the best way to go.


Side Effects and Dangers of HGH Abuse


HGH has been shown, in some studies, to have side effects which include Carpal Tunnel Syndrome, Arthritis, edema (swelling), water retention, joint pain, Gigantism (unnatural bone growth) and bloating. Side effects are typically experienced with high dose abuse over long periods of time.


One should also completely avoid HGH if they have cancer or a high risk or prevalent family history of cancer, especially prostate and reproductive cancer. HGH stimulates cell reproduction and regeneration, which can have a dangerous effect on one who has cancer.


Long term abuse of HGH can also cause the Pituitary Gland to produce less HGH for a while, how long depends on the person, lifestyle and the abuse level. Studies have shown, the pituitary gland has the ability to produce healthy levels of human growth hormone when stimulated through out the entire human life span.




Avoid Side Effects


Initially: Numerous studies have shown side effects can be avoided by slow initial administration, proper monitoring of levels and usage of HGH on a daily basis in what is called a low-dose, high-frequency method.


Ongoing: Side effects can be avoided in an HGH replacement therapy program when one avoids high doses of HGH over a long period of time and continues to monitor their blood by getting bi-yearly blood work analysis (see recommended blood panel).




Typical Protocol of HGH


A typical protocol utilizing low doses has shown to have the best effects.


General Range: A generic protocol for someone over the age of 35, deficient in HGH/IGF-1, and showing signs of Andropause (see symptoms of Andropause), is approximately 1 to 2 IU per day, with five days on (Monday through Friday using 1IU per day) and two days off (Saturday and Sunday no usage of HGH). This is not an exact, but only a general range.


In order to come up with a more precise HGH therapy protocol, the physician must review the patients current blood work analysis, physical exam (including blood pressure, height, weight and age), medical questionnaire for reviewing patients medical history, life style and patient personal health goals.


Avoid body builder doses of 3 or more IU per day.




What is the Best time of Day to Inject HGH


Some research has shown the best time to take HGH injections is in the morning, upon awakening. Other research has also shown the majority of naturally produced HGH is pulsed from the Pituitary Gland at night. This has led to further studies showing that a once-a-day injection at night seem to have the most beneficial effect, while some have found injections in the morning provide the best results. A third option is distributed dosing.


Distributed Dosing: Using Two or More Injections of HGH a Day


Some researchers have administered HGH injections twice daily. A typical dose is split up, once in the morning upon awakening, and once at night before going to sleep.




The 2 low dose method:


1. In the 2 low dose method approach, when a small dose is used before working out and then again after working out, people have reported the best gains in physical regeneration, regenerating the muscles, burning fat, improving body composition and physic.


2. Others have reported when doing the 2 low dose method of getting the best results when they do a small dose in the morning on an empty stomach and then again 30 minutes before going to sleep. They reported excellent sleep, and general feeling of well being, focus and energy during the day and depression was also decreased.


Generally however, most typical protocols recommend one time per day for convenience and so that patients don't feel like they are a "pin cushion".




Best Results using Injectable HGH: Human Guide to Longevity and Cell Regeneration Medicine & Understanding these most Crucial Elements


An HGH protocol that works best for you must be customized to your height, weight, age, blood work, physical exam and medical history. There is no one-size-fits-all program when doing an HRT (Hormone Replacement Therapy) program using HGH.


In general, to get the best results in an HGH replacement therapy program, incorporate a consistent health conscious lifestyle:


  1. Intense Regular Exercise: including cardiovascular exercise 45 minutes a day, 4 days a week, and weight lifting, every other day (four days a week) upper and lower body on alternating days. If time is a factor and depending on your own busy work schedule and life style, try to at least exercise a minimum of four to six times a week, doing aerobic activities (running, jogging, bicycling, dancing), in conjunction with some weight training. HGH can increase ones appetite and metabolism, exercise has been found to be the best way to help quench hunger and cravings - good nutrition with high nutrient density and 5 to 6 small meals a day is another way to quench the increase in hunger that can sometimes be caused by HGH.


  2. HGH & Supplements: Most RDA recommendations for vitamins, minerals and supplements in general are insufficient. Take a comprehensive multivitamin and mineral complex, vitamin D and calcium supplements, amino acids (help stimulate natural hgh production), good brain formula and omega 3 (fish oil) supplements. And get a good healthy dose of sunlight, 30 minutes per day for overall vitamin D synthesis, Ocean water also has a lot of healthy amount of minerals which are excellent for the skin.


  3. HGH and Diet Recommendations: a low caloric diet of raw, warm and steamed foods, do not go more than 3 hours during a day without eating something, & 8 large glasses of water per day.

    Eat five to six small meals per day. Strictly follow a healthy, nutritious, nutrient-dense, and calorie-restricted diet. Limit consumption of sugar (a study showed that sugar diminishes HGH secretion).

    Several studies have shown that being overweight and suffering from obesity can significantly shorten one's lifespan, and lead to a higher incidence of a host of diseases - especially cancer.

    Repeated studies have shown that moderate caloric restriction can prolong lifespan up to 30% in humans and animals.

    The best diet based on human evolution, is one involving eating raw foods; eating enough fresh fruits, raw and steamed vegetables, nuts, grains and seeds.

    Avoid processed foods to the best of your ability.

    Try to eat organic foods, because non-organic foods have pesticides which can cause genetic damage and upset your hormone levels. Therefore, eat enough calories from organic fruits, vegetables, meat, eggs and fish at a range which will not put your body in starvation mode (consult doctor). Try to avoid alcohol, caffeinated or carbonated drinks, processed cereal fiber, non-organic milk products.

    Make fighting obesity the central focus of your diet. Fat tissue is rich in Aromatase enzymes, and converts testosterone to estradiol and inactivates testosterone. Estradiol (17β-estradiol, also oestradiol) is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans.




HGH and Exercise: Exercise Stimulates Natural HGH Production


Regular exercise is the best way to naturally increase you HGH production and your body's ability to process it. Moreover, aging is associated with weaker muscles, lower bone mass and less flexibility. Therefore making stretching (like yoga) a part of your daily routine. Several studies have shown that exercise prolongs life, decreases heart disease, and lowers high blood pressure and stroke rates. Aerobic exercise is very important for maintaining a healthy vascular system, which is a central factor in longevity, vitality and health.



HGH and Dietary Supplements


Take adequate amounts of nutrients and supplements. Take a good multi-vitamin that requires you to take more than one vitamin per day, so the supplements are spread out over a given day. Be sure your supplement regimen has enough anti-oxidants. The RDA (Recommended Daily Allowance) is usually insufficient for the desired health effects. In the American Academy of Anti-Aging Medicine Desk Reference you can find out about the recommended doses. Take the time to do the research. You might also want to get blood work done to see which vitamins and minerals your body has a problem metabolizing, and think about increasing those specific vitamin and minerals.



Hormone Replacement Therapy and HGH Optimization


Hormone Optimization or Bio-Identical Hormone Replacement Therapy comes in many forms, programs and therapies. This might be remembered in history as the stage or period of medical anti-aging, longevity and disease prevention, just before the next great breakthrough in medicine of human genetic engineering (less than 30 years away). Genetic science promises to extend human life beyond 10 fold.

Pursuing HRT (for people over 30 years of age), is fast becoming the single most popular medical protocol sought out for slowing down the aging process, regenerating the body, even reversing the aging process, and, in some circumstances, extending one's lifespan, youthfully, and with vigor and vitality.

One of the greatest discoveries to date, for living a long, healthy and youthful life, is to ensure you have healthy levels and a balance of hormones in your body. Maintaining healthy levels of hormones in your body based on your height, weight, age and blood work, along with radically healthy lifestyle changes, can potentially extend your lifespan 10 to 20 years, that doesn't mean you live longer as an older person, you live longer because you have slowed down the aging process, and live more youthfully as you progress through life.


Make sure your hormones are balanced. Even if you are under the age of 30, having your hormone levels and blood work checked every six months is of great value in order to know your "baseline values". If you are older than 30, balancing your hormones and changing your lifestyle will help you overcome many age related symptoms, such as being overweight, suffering from depression, andropause, peri-menopause, low libido, infertility and many other age-related symptoms.


Research has shown that utilizing testosterone, DHEA, HGH, and other hormones for those deficient and older than 30, can have a protective effect on aging, and several studies indicate, can increase lifespan.




Is Human Genetic Engineering the Next Stage of Anti-Aging Medicine after HGH, Testosterone and HRT?


The Human Genome Project was a $3 billion sequencing project funded by the US government in 1990. Its goal was to identify, sequence and label each rung in the genetic spiral staircase in the entire human genome - the human genetic equation. With that project completed on or about 2000, many profound new discoveries have been made, and therefore, it is estimated human genetic engineering and gene therapy will have their kinks worked out and become affordable and mainstream around the year 2035.


Human genetic engineering is going to change human life, anti-aging and longevity medicine, so radically, it is nearly impossible to imagine how profound the results will change medicine and civilization. In theory, human genetic engineering works like this, each breakthrough in genetic science should extend your lifespan long enough for the next major breakthrough to come, which would extend your lifespan even longer. The accumulated life extension of future biotechnology, bioscience, bioengineering and human genetic engineering should theoretically provide a kind of longevity on the plateau of immortality (potentially).




Therefore, the next stage, era or period of anti-aging medicine after Hormone Optimization aka HRT, will be called HGE or HGO (Human Genetic Engineering or Human Genetic Optimization), promises to extend the human lifespan more than just 10 to 20 years. The youthfulness, that HRT promotes and promises, could potentially extend human lifespans more than 10++ fold. Currently, scientists modifying the DNA of non-human species have found novel ways of extending youthful living in animals, insects, bacteria and yeast up to eight to 10 fold. When scientists can consistently do this for monkeys, humans will be next. This kind of science is right around the corner.









HGH and Testosterone


Testosterone is an important hormone for both males and females. It protects the cardiovascular system, fights obesity, develops and maintains reproductive health and sexual potency, supports the brain, bones and muscles, and improves mood and memory. Testosterone production by the ovaries, adrenals, testicles, and even the conversion to testosterone on peripheral tissues (from DHEA, androstenedione), all decline with "normal" aging.


Contact me if you have any recommendations on how to improve this article: profmark@gmail.com


Bibliography



1. Reichlin S: Regulation of somatotrophic hormone secretion.
In: Greep RO, Astwood EB, Knobil E, et al.,
eds. Handbook of Physiology, Section 7, Endocrinology,
Vol. IV. The Pituitary Gland and Its Neuroendocrine
Control. Washington, DC: American Physiological Society,
974:405-448.



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